Calcitriol, the active metabolite of Vitamin D3, plays a critical role in:
Calcitriol is naturally synthesized in the kidneys from 25-hydroxycholecalciferol and is essential for bone health and calcium-phosphorus balance.
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Dosing recommendations are based on serum calcium levels and the condition being treated.
Post-menopausal Osteoporosis:
Renal Osteodystrophy (dialysis patients):
Hypoparathyroidism and Rickets:
Secondary Hyperparathyroidism (Pre-dialysis):
Intravenous administration:
- Children:
- Pre-dialysis secondary hyperparathyroidism: Initial dose is 10–15 ng/kg/day for children <3 years.
- Elderly:
- No specific dose adjustments are required.
Early side effects:
Late side effects:
Injection-related side effects:
Thiazide diuretics:
Digitalis treatment:
Magnesium-containing drugs:
⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.