Colitrol IV Injection | 1mcg/ml | ePharma
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Colitrol IV Injection

Generic: Calcitriol

Type: Injection

Pack Size: 1 Pc

Calcitriol, the active metabolite of Vitamin D3, plays a critical role in:

  • Promoting intestinal calcium absorption.
  • Regulating bone mineralization.
  • Maintaining calcium homeostasis, including stimulating osteoblastic activity in the skeleton.

Calcitriol is naturally synthesized in the kidneys from 25-hydroxycholecalciferol and is essential for bone health and calcium-phosphorus balance.

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✅ Description:

Pack Image of Colitrol 1 mcg Injection
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✔️ Colitrol is indicated for the management of:
  • Post-menopausal osteoporosis
  • Renal osteodystrophy
  • Postsurgical hypoparathyroidism
  • Idiopathic hypoparathyroidism
  • Pseudohypoparathyroidism
  • Secondary hyperparathyroidism in moderate to severe chronic renal failure (pre-dialysis)
  • Vitamin D-dependent rickets
✔️ Dosage & Administration

Dosing recommendations are based on serum calcium levels and the condition being treated.

Post-menopausal Osteoporosis:

  • Oral dose: 0.25 mcg twice daily.

Renal Osteodystrophy (dialysis patients):

  • Initial dose: 0.25 mcg daily.
  • For normal or slightly reduced calcium levels: 0.25 mcg every other day may suffice.

Hypoparathyroidism and Rickets:

  • Initial dose: 0.25 mcg/day (in the morning).
  • If no response in 2–4 weeks, increase the dose at 2–4-week intervals.

Secondary Hyperparathyroidism (Pre-dialysis):

  • Adults and children aged ≥3 years: 0.25 mcg/day, increased to 0.5 mcg/day if needed.
  • Children aged <3 years: 10–15 ng/kg/day.

Intravenous administration:

  • Initial dose: 1 mcg (0.02 mcg/kg) to 2 mcg three times weekly (every other day).
  • Doses can range from 0.5 mcg to 4 mcg based on severity and response.
  • Dose adjustments should occur at 2–4-week intervals.
  1. Children:
    • Pre-dialysis secondary hyperparathyroidism: Initial dose is 10–15 ng/kg/day for children <3 years.
  2. Elderly:
    • No specific dose adjustments are required.
✔️ Side Effects

Early side effects:

  • Weakness, headache, somnolence, nausea, vomiting, dry mouth, constipation, muscle pain, metallic taste.

Late side effects:

  • Polyuria, polydipsia, anorexia, weight loss, conjunctivitis (calcific), pancreatitis, photophobia, pruritus, nocturia, rhinorrhea, cardiac arrhythmias, and rarely psychosis.

Injection-related side effects:

  • Occasional mild pain at the injection site.
✔️ Interaction

Thiazide diuretics:

  • Risk: Increases hypercalcemia risk.
  • Recommendation: Monitor calcium levels closely.

Digitalis treatment:

  • Risk: Hypercalcemia may precipitate cardiac arrhythmias.
  • Recommendation: Use with caution.

Magnesium-containing drugs:

  • Risk: May cause hypermagnesemia.
  • Recommendation: Avoid concurrent use.
✔️ Contraindications
  • Known hypersensitivity to any component of Colitrol.
  • Diseases associated with hypercalcemia.
✔️ Pregnancy & Lactation
  • Pregnancy: Use only if benefits outweigh potential risks.
  • Lactation: Serum calcium levels of mother and infant should be monitored during breastfeeding.
✔️ Precautions & Warnings
  • Avoid excessive dosage as it may cause hypercalcemia and, in some cases, hypercalciuria.
  • Use cautiously in patients receiving digitalis to prevent cardiac arrhythmias.
  • Discontinuation may cause a rebound effect; adjust the dose downward carefully.
  • Vitamin D and its derivatives should not be administered during Colitrol therapy.
  • Chronic hypercalcemia can lead to:
    • Generalized vascular calcification.
    • Nephrocalcinosis.
    • Soft tissue calcification.
  • Use a non-aluminum phosphate binder to control serum phosphorus levels in dialysis patients.
✔️ Storage Conditions
  • Store in a dry place, away from light and heat.
  • Keep out of reach of children.
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Delivery typically takes 1-2 business days, depending on your location.

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Check our pricing section for Colitrol IV Injection price in Bangladesh. After Submitting Order, You may receive phone call for verification, price and delivery confirmation. We deliver inside/outside Dhaka (Delivery all over Bangladesh). We offer express/urgent medicine delivery inside Dhaka. Do not forget to check discount/cashback offers if you are eligible to avail any.

⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.

📦Pricing Information, Availability:
Product Availability & Pricing Notice Please note that pricing, availability, and service offerings are subject to change due to: Market fluctuations, Manufacturer or supplier adjustments, Product discontinuation or temporary unavailability, Advertising errors. All orders depend on stock availability and staff resources. If services are provided on a time-and-materials basis, any shared estimates are for planning purposes only.

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